16 results
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... adsorption onto cancer cells ... #treatment #hematology ... #differential
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
WBC >100k, + lab signs ... organ damage • Treatment ... Lysis of tumor cells ... TLS #diagnosis #management ... #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Framework and Management ... symptoms: - Muscle pain ... - Abdominal pain ... kidney tubular cells
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Release from blast cells ... initiation • Differential ... APML #diagnosis #management
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of congestion ... acute coronary syndrome ... #diagnosis #differential ... #algorithm #management ... #table #foamed
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Arthritis, AS Treatment ... Nonsurgical abdominal pain ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... , breast bone, pelvis ... and lower jaw Treatment ... #Rheumatology # ... diagnosis #management
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... paresthesia, abdominal pain ... disease flares: • Prevention ... #diagnosis #management ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... Diagnosis: HLH signs ... agent are the main ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... tissue: Epithelioid cells ... Self-limiting, chronic but stable ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms