17 results
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... and laboratory diagnosis ... polychromatophilic cells ... #Hematology #Pathology ... #Smear #Microscopy
Some of the techniques used for Antenatal Diagnosis

Amniocentesis 
 - Chromosome/micro-array and DNA analysis 
 -
— PCR Fetal blood ... haemoglobin for anaemia ... - Fetal infection ... genetic analysis of cells ... surgery, e.g. laser photo-coagulation
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... • Parvovirus infection ... abnormal under a microscope ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... = funny-shaped cells ... cytopenias (usually anemia ... risk-stratification • Risks: infection ... #hematology #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... result from low blood ... #oncology #hematology ... #diagnosis #management
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
anemia • Cold ... Immunoglobulin M (IgM) • Blood ... sensitize red blood ... cells (RBCs) at ... #hematology #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... cells + production ... Auto-amplification loop Diagnosis ... #management #treatment ... #summary #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... pain, bleeding, infections ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Weight loss • Anemia ... Immune hemolytic anemia ... classification #hematology ... #oncology #management
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
lymphocytes, smudge cells ... 5) Symptoms of anemia ... Complications: 1) Infection ... Leukemia #oncology #hematology ... #management