10 results
A normal peripheral blood smear indicates the appropriate appearance of red blood cells, with a zone
A normal peripheral ... blood smear indicates ... cells, with a zone ... #Clinical #Path ... #Microscopy #PeripheralBloodSmear
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... #Blood #Smear # ... Analysis #hematology ... #microscopy #interpretation ... #clinical #anemia
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... including peripheral ... blood myeloid cells ... NEJM Review: https
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... polychromatophilic cells ... hemolytic #anemia #Hematology ... Pathology #Smear #Microscopy
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
bone marrow and peripheral ... leukopenia) Peripheral ... abnormal under a microscope ... differential • Peripheral ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or ... Pruritis after hot bath ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Aplastic Anemia Clinical ... anemia) Labs: • Peripheral ... result from low blood ... Anemia #oncology #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... cytometry • Peripheral ... Lymphocytosis: Absolute blood ... • Richter’s Syndrome ... workup #oncology #hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... ducts Clinical ... neuropathy • Peripheral ... Pulmonary amyloidosis, PAH ... Nephrogenic DI Hematologic
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Clinical suspicion ... Amyloidosis Clinical ... : • Nephrotic syndrome ... Diagnostic Testing Blood ... polarized light microscopy