9 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... : Sickle cell disease ... #Smear #Analysis ... #hematology #microscopy
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
Red cell autoagglutination ... individual’s red blood ... cells (RBCs or ... Clinical #Path #Blood ... #Smear #Microscopy
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
Red cell autoagglutination ... individual’s red blood ... cells (RBCs or ... Clinical #Path #Blood ... #Smear #Microscopy
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... non-specific red cell ... polychromatophilic cells ... arrow) Peripheral smear ... #Microscopy
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
• Peripheral blood ... smear + DAT + further ... History • Bite cells ... DAT (-) → Sickle Cell ... & microcytic RBCs
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
cell count (anemia ... Peripheral Smear ... abnormal under the microscope ... abnormal under a microscope ... smear • Bone marrow
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... • Peripheral smear ... : Smudge cells or ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
• Symptoms of anemia ... Immunoglobulin M (IgM) • Blood ... smear - RBC agglutination ... sensitize red blood ... cells (RBCs) at
Babesiosis on Peripheral Smear
85 M from SE USA, hx splenectomy, IgG4 plasmacytic syndrome: F, chills, profound
clindamycin & quinine, rbc ... post exchange: blood ... inclusions >10%RBC ... like illness, red cell ... lysis: fever, anemia