12 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... : Sickle cell disease ... #Smear #Analysis ... #hematology #microscopy
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
Red cell autoagglutination ... individual’s red blood ... cells (RBCs or ... Clinical #Path #Blood ... #Smear #Microscopy
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
Red cell autoagglutination ... individual’s red blood ... cells (RBCs or ... Clinical #Path #Blood ... #Smear #Microscopy
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... smear or on bone ... - infiltrates (anemia ... • Peripheral smear ... Leukemia #Hematology #Oncology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... non-specific red cell ... polychromatophilic cells ... arrow) Peripheral smear ... #Microscopy
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
• Peripheral blood ... smear + DAT + further ... History • Bite cells ... DAT (-) → Sickle Cell ... & microcytic RBCs
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... • Peripheral smear ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... diagnosis #workup #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
cell count (anemia ... Peripheral Smear ... abnormal under a microscope ... smear • Bone marrow ... diagnosis #hematology #oncology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
• Symptoms of anemia ... Immunoglobulin M (IgM) • Blood ... smear - RBC agglutination ... sensitize red blood ... cells (RBCs) at
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytic Leukemia (CLL ... • Peripheral smear ... lymphocytes, smudge cells ... 5) Symptoms of anemia ... Lymphocytic #Leukemia #oncology