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diagnosis hematology acidosis causes lactic oncology chronic diarrhea hemolytic typea typeb agglutinin algorithm cell cold criticalcare dementia disease elevation geriatrics
Lactic Acidosis - Classification and Differential Diagnosis Type A Lactic Acidosis: Inadequate Oxygen Delivery • Anaerobic muscular
Lactic Acidosis - Classification ... and Differential ... delivery: Hypoxemia, Anemia ... #Differential # ... #TypeA #TypeB #lactate
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... e.g., uptake by cells ... 30mmHg) - Severe anemia ... Acidosis #Elevation #Differential ... #typea #typeb #classification
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Lactic Acidosis - Differential ... Shock, Severe Anemia ... Beta-Agonists, ↑ work ... with negative lactate ... Lactic #Acidosis #Differential
Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
Diagnosis and workup ... the diagnostic workup ... - Progressive amnesia ... MNCD #Dementia #Differential ... #Subtypes #Classification
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Algorithm • Sickle cells ... #Differential # ... Diagnosis #Algorithm #workup
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... abnormal under the microscope ... abnormal under a microscope ... Workup: • Complete ... blood count with differential
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... -95% of cases) Classification ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... immune hemolytic anemia ... elevation Serum lactate ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... • hemolytic anemia ... Hyperbilirubinemia • Elevated lactate ... younger pts) Differential ... sensitize red blood cells
Causes of Chronic Diarrhea - Differential Diagnosis Osmotic • Food/Drink: Lactose intolerance, Artificial sweeteners (e.g. sorbitol, high
Chronic Diarrhea - Differential ... • Food/Drink: Lactose ... Secretory: • Microscopic ... Diarrhea #Causes #Differential ... #inflammatory #classification
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