22 results
diagnosis hematology oncology management clinical differential syndrome hemolytic leukemia photo workup chronic cll eschar lymphocytic mds myelodysplastic rheumatology skin smear
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Megaloblastic Anemia ... Sickled red cells ... disease Bite cells ... Smear #Analysis #hematology ... #microscopy #interpretation
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Neutropenia - recurrent infections ... Idiopathic • Infections ... and thymoma DDX ... #oncology #hematology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic anemia ... Microangiopathic hemolytic anemia ... polychromatophilic cells ... #Hematology #Pathology ... #Smear #Microscopy
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Mean age at Dx ... petechiae) • Frequent infections ... DDX: Rule Out ... • Parvovirus infection ... Syndromes #diagnosis #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Avg age of DX ... disease • Infectious ... autoimmune hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... • hemolytic anemia ... sensitize red blood cells ... disease #hemolytic #anemia ... #hematology #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... cytopenias (usually anemia ... risk-stratification • Risks: infection ... Management #treatment #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
weeks without infection ... Scoring system: DDX ... • Neutropenia, anemia ... Contamination, colitis DDX ... workup #oncology #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle cells ... inclusions - If infection ... ARUPLabs #Hemolytic #Anemia ... Algorithm #workup #hematology
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Bandemia, AKI. ... Dx? ... When considering infections ... bacillus cause selsis ... Canimorsus #Skin #Rash #dermatology
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