17 results
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
involving the arms ... revealed 25% plasma cells ... Wright–Giemsa stain) #Clinical ... #HONC #Derm #Plasmacytomas ... Leukemia #Smear #NEJM
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Skin: - CLL cells ... smear: Smudge cells ... or basket cells ... #Leukemia #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... , smudge cells are ... immunophenotype Clinical ... Transformation to large cell ... hematology #hemeonc #diagnosis
Macroglossia in Light-Chain Amyloidosis- Physical examination revealed macroglossia, with indentations from the teeth (Panel A)...A biopsy
findings confirmed a diagnosis ... under polarized microscopy ... Early diagnosis ... #clinical #photo ... AL #lightchain #NEJM
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Clinical suspicion ... Clinical Manifestations ... Lymphocyte Proliferation ... Increased plasma cells ... polarized light microscopy
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
Leukemia Clinical ... required for dx - T-cells ... Same morphologic/clinical ... disease but cells ... are NK cells (sCD3
Immunosuppressive Strategies for the Prevention or Treatment of Acute GVHD. Panel A shows several classic immunosuppressive
in routine clinical ... been tested in clinical ... of activated T cells ... Pathophysiology #IM ... #Honc #Pharm #GVHD
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... and laboratory diagnosis ... non-specific red cell ... polychromatophilic cells ... Pathology #Smear #Microscopy
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from mature B cells ... presence of Hodgkin's cells ... Reed-Sternberg cells ... Hodgkin Lymphoma - Clinical ... • The tumor cells
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
aggregate foci (>50 cells ... aggregate) of CD4 T cells ... , B cells, and plasma ... cells around salivary ... ducts Clinical