11 results
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Beautiful acanthocytes/spur cells in a patient with McLeod Syndrome. X-linked disorder characterized by reduced expression of
acanthocytes/spur cells ... patient with McLeod Syndrome ... SpurCells #McLeod #Syndrome ... #Smear #Pathology ... #Microscopy #Clinical
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
dipstick, urine microscopy ... Abdominal compartment syndrome ... including blood culture ... , urine culture, ... • Cardio-renal syndrome
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... abnormal under the microscope ... abnormal under a microscope ... blood count with differential ... Peripheral blood smear
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... adsorption onto cancer cells ... disorders • Shear ... vonWillebrand #Syndrome ... treatment #hematology #differential
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... Normal Blood Smear ... Myelodysplastic Syndromes ... Macrocytosis, Target Cells ... #elevatedMCV #Differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... IgM) • Blood smear ... younger pts) Differential ... sensitize red blood cells
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... Multinucleated giant cells ... (PR3-ANCA)): Microscopic ... #Vasculitis #Differential
Fever After International Travel

Infectious Disease:
• Endemic in either the destination or home region

Viral Syndromes:
Arboviral infections, a
function • Blood culture ... chest film; blood-smear ... dipstick test, microscopic ... examination, culture ... Fever #Travel #Differential
Causes of Chronic Diarrhea
Osmotic Diarrhea
 1. Medications: antacids, lactulose, sorbitol
 2. Disaccharidase deficiency: lactose intolerance
 3.
Zollinger-Ellison syndrome ... Microscopic colitis ... Malabsorption syndromes ... Cryptosporidium, Isospora belli ... Diarrhea #Causes #Differential