12 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... EricsMedicalLectures/ #Peripheral ... #Blood #Smear # ... Analysis #hematology #microscopy
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... polychromatophilic cells ... (black arrow) Peripheral ... smear changes are ... #Microscopy
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
- Differential ... Hereditary: • Peripheral ... blood smear + DAT ... History • Bite cells ... #Differential #
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Smear: • Dysplastic ... count with differential ... • Peripheral blood ... smear • Bone marrow ... diagnosis #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Diagnosis: • Peripheral ... smear → small rnature-appearing ... 5) Symptoms of anemia ... Lymphocytic #Leukemia #oncology ... hemeonc #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
blasts in the peripheral ... blood smear or ... - infiltrates (anemia ... smear: Blasts ... Leukemia #Hematology #Oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... ) Labs: • Peripheral ... result from low blood ... #oncology #hematology ... #diagnosis #management
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
smear - RBC agglutination ... younger pts) Differential ... sensitize red blood ... cells (RBCs) at ... passage of red-brown urine
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
cytometry • Peripheral ... smear: Smudge cells ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... diagnosis #workup #oncology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Immunohistochemical studies (to differentiate ... classification #hematology #oncology ... #management