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diagnosis oncology management derm algorithm anemia angiosarcoma aplastic breast causes chronic classification cll coagulation dic disseminated hemophagocytic hlh hodgkins intravascular
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
A peripheral-blood ... revealed 25% plasma cells ... Wright–Giemsa stain) #Clinical ... #HONC #Derm #Plasmacytomas ... #Smear #NEJM
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
lymphadenopathy • Blast cells ... Rapidly rising blast cells ... : Granulocytic cells ... Cells are in the ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
- Summary Cancer ... Orange or Hep C Clinical ... Skin: - CLL cells ... smear: Smudge cells ... or basket cells
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cells, red ... blood cells or ... cells - red blood ... cells, white blood ... Syndromes #diagnosis #hematology
Radiation-Induced Angiosarcoma after Breast-Cancer Treatment - Physical examination revealed an area of skin 10 cm in
Angiosarcoma after Breast-Cancer ... Treatment - Physical ... #Clinical #Derm ... #Honc #Path #RadiationInducedAngiosarcoma ... #NEJM
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 T cells ... Phagocytosis of blood ... cells + production ... accumulation of clinical ... B-LNH), solid cancers
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from mature B cells ... Hodgkin Lymphoma - Clinical ... B cells ... Hodgkin Lymphoma Treatment ... classification #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
hematopoietic stem cells ... number of CD34+ cells ... cellularity + dysplastic cells ... number of CD34+ cells ... Number of CD34+ cells
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... ABO incompatible blood ... organ damage Clinical ... Schistocytes, helmet cells ... #management #hematology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
From Blood Cancer ... acute myeloid leukemia ... with repeated red cell ... importance of clinical ... #algorithm #hematology
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