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diagnosis oncology clinical management myelodysplastic anemia chronic derm lymphocytic myelodysplasia pathology peripheral plasmacell plasmacytomas prolymphocytes syndrome syndromes treatment workup
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
lymphadenopathy • Blast cells ... Rapidly rising blast cells ... : Granulocytic cells ... Cells are in the ... #Hematology #Oncology
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
Plasmacytomas and Plasma-Cell ... A peripheral-blood ... 25% plasma cells ... stain) #Clinical #HONC ... #Smear #NEJM
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
- Summary Cancer ... cells can infiltrate ... : Smudge cells or ... basket cells can ... aplasia • ITP
Prolymphocytes In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML). 🔬Tumor
🔬Tumor cells are ... size lymphoid cells ... Prolymphocytes #Smear ... Peripheral #Pathology #Microscopy ... #Clinical #Blood
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
by blood cells ... • Anemia • Aplastic ... blood cells, red ... blood cells or ... cells - red blood
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... transformation to acute leukemia ... Allogeneic stem cell ... Myelodysplastic #Syndrome #MDS ... Management #treatment #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
hematopoietic stem cells ... number of CD34+ cells ... cellularity + dysplastic cells ... number of CD34+ cells ... Number of CD34+ cells
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