47 results
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
Plasmacytomas and Plasma-Cell ... revealed 25% plasma cells ... stain) #Clinical #HONC ... Leukemia #Smear #NEJM
Signaling Mechanism of PD-1 and PD-L1 and Inhibition of PD-1 Signaling in Microsatellite-Instability–High Cancers. MHC1 denotes
Microsatellite-Instability–High Cancers ... histocompatibility complex 1 #Pathophysiology ... #Honc #Pharm #PD1 ... MicrosatelliteInstability #NEJM
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
and activate them ... or plasma cells ... neutralizing them - Activate ... Complement: Abs activate ... Humoral #Immunity #pathophysiology
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Airway epithelial cells ... antigens and thereby activate ... naive CD4 T cells ... These T cells then ... #asthma #pathophysiology
Activated T-Cell Killing a Cancer Cell

#TCell #Killing #Cancer #Cells #clinical #microscopy #video
Activated T-Cell ... Killing a Cancer ... #Killing #Cancer ... #Cells #clinical ... #microscopy #video
Activated T-Cell Killing a Cancer Cell

#TCell #Killing #Cancer #Cells #clinical #microscopy #video
Activated T-Cell ... Killing a Cancer ... Cell #TCell #Killing ... #Cancer #Cells ... #clinical #microscopy
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Particular CD4+ Th cells ... harmful -> Th Cells ... activate macrophages ... , mast cells or ... Allergy #Immunology #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
with cytotoxic T cells ... natural killer cells ... antigen - TH1 cells ... cytokines, which activate ... Classification #Pathophysiology
Hemolysis in Hereditary Spherocytosis. Panel A shows the structure of a normal red cell and a
spleen in which red cells ... between endothelial cells ... #Pathophysiology ... #Honc #IM #Spherocytosis ... HereditarySpherocytosis #NEJM
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Natural Killer Cells ... • Humoral: (B cell ... : (T cell response ... activity #Inflammatory ... #Inflammation #pathophysiology