85 results
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... criteria for 1) hematologic ... peripheral blood myeloid ... cells NEJM Review ... Autoinflammatory #Somatic #rheumatology
Multiple Myeloma - Treatment Algorithm
a) Newly Diagnosed Myeloma: Transplant Eligible
b) Newly Diagnosed Myeloma: Transplant Ineligible

doi: 10.1038/s41408-020-00359-2

#Multiple
Multiple Myeloma ... Algorithm a) Newly Diagnosed ... Myeloma: Transplant ... Eligible b) Newly Diagnosed ... Algorithm #management #hematology
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
case of acute myeloid ... AML #Clinical #Hematology ... #Pathology #Smear
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
other forms of myeloma ... Clinical #Smear #Hematology ... #Pathology
Diagnosis of active multiple myeloma is not just CRAB; it's actually "SLiM CRAB" @Majorajay & @Vincentrk

#MultipleMyeloma
Diagnosis of active ... multiple myeloma ... Oncology #HemeOnc #Hematology ... Anemia #Clinical #Diagnosis
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
- Differential Diagnosis ... Non-infectious (malignancy, rheumatologic ... Myelofibrosis • Chronic Myeloid ... #Differential #Diagnosis ... causes #Platelets #hematology
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Pathologic Red Blood ... Atlas #Microscopy #Pathology ... #Hematology #Diagnosis ... Robbins & Cotran Pathologic
Dysmorphic Red Blood Cells on Electron Microscopy
This eyeSCANdy image shows dysmorphic red blood cells from the
Dysmorphic Red Blood Cells ... dysmorphic red blood cells ... SEM #clinical #pathology ... #hematology #nephrology
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
Sezary #Syndrome #Cells ... #Clinical #Pathology ... Smear #Microscopy #Hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
- Differential Diagnosis ... Features of hematologic ... predominant immature cells ... #Differential #Diagnosis ... #Algorithm #hematology