6 results
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... e.g. lymphoma, multiple ... myeloma, Waldenstrom ... #Management #treatment ... #hematology #differential
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
involvement, unique or multiple ... increased IgG4+ cells ... " Treatment: ... management #phenotypes #workup ... #treatment #rheumatology
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
- Differential Diagnosis ... lymphocytes, plasma cells ... the mainstay of treatment ... the setting of multiple ... myeloma or AL amyloidosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... , or all three myeloid ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
patients with EMD myeloma ... IFE, FLC assay Pathology ... Bone marrow Treatment ... • Multiple myeloma ... #Workup #Hematology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... syndrome): - Hematologic ... Leukostasis: - Usually myeloid ... Oncology #HemeOnc #Diagnosis