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oncology hematology cell gammopathy management monoclonal plasmacytoma significance solitary undetermined workup
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Multiple Myeloma ... hypercalcemia) • Anemia ... osteolytic lesions and pathologic ... marrow plasma cells ... #Myeloma #Diagnosis
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
No evidence of anemia ... progress to IgM multiple ... insufficiency, Anemia ... progression to multiple ... Significance #hematology #diagnosis
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Diagnosis? ... • No CRAB - no anemia ... patients with EMD myeloma ... IFE, FLC assay Pathology ... • Multiple myeloma
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