41 results
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
thromboembolic disease ... hematopoietic stem cells ... including peripheral blood ... myeloid cells ... NEJM Review: https
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... anemia, Liver diseases ... Myelodysplastic syndrome ... , Liver diseases ... Hemolytic uremic syndrome
Sickle cells
These photos show sickle cells on peripheral blood smears. In the left photo target cells
photos show sickle ... blood smears. ... to sickle cell disease ... thalassemia, and HbSC disease ... Path #BloodSmear #Blood
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myeloproliferative Disease ... cells, red blood ... cells - red blood ... cells, white blood
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Sickle-cell disease ... cells that adopt ... These cells can ... Sickle cell disease ... The underlying pathophysiology
Castleman's Disease and Associated Syndromes
HYALINE VASCULAR VARIANT
 • unicentric, HHV8-ve, children and young.
 • Hyalinized vessels
Castleman's Disease ... and Associated Syndromes ... • Hyalinizeä blood ... Diffuse plasma cells ... Pathogenesis "IL6 syndrome
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Sickle Cell Disease ... - Pathophysiology ... the sickle red cells ... obstructing and reducing blood ... #Pathophysiology
Some of the techniques used for Antenatal Diagnosis

Amniocentesis 
 - Chromosome/micro-array and DNA analysis 
 -
— PCR Fetal blood ... serology - Fetal blood ... genetic analysis of cells ... surgery, e.g. laser photo-coagulation ... transfusion syndrome
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... Chronic pulmonary diseases ... coronary heart disease ... Acute Coronary Syndrome ... Differential #Diagnosis #Pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
natural killer cells ... - Red blood cell ... with mismatched blood ... during hemolytic disease ... Classification #Pathophysiology