57 results
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
and Plasma-Cell Leukemia ... A peripheral-blood ... revealed 25% plasma cells ... Plasmacytomas #PlasmaCell #Leukemia ... #Smear #NEJM
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... - Blood and Bone ... - Blood & BM • ... develop leukostasis syndrome ... • Tumor lysis syndrome
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
defined as white blood ... in peripheral blood ... the margins of blood ... Leukemoid reaction ... Leukemoid Reaction
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
T-prolymphocytic leukemia ... Acute Myeloid Leukemia ... 🔬Tumor cells are ... size lymphoid cells ... Microscopy #Clinical #Blood
The hematopoietic tree and the resulting leukemias and lymphomas 
The hematopoietic tree refers to the hierarchical
organization of blood ... into all types of blood ... gives rise to red blood ... types of white blood ... production of immature blood
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Skin: - CLL cells ... or basket cells ... Lymphocytosis: Absolute blood ... • Richter’s Syndrome ... • Sezary syndrome
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... cells, red blood ... cells - red blood ... cells, white blood
The arrows point to blister cells. These cells are thought to be precursors of helmet cells.
point to blister cells ... These cells are ... precursors of helmet cells ... The photo on the ... Path #BloodSmear #Blood
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... similarly to mast cells ... Chronic myeloid leukemia ... Acute myeloid leukemia ... Acute basophilic leukemia
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... hematopoietic stem cells ... including peripheral blood ... myeloid cells ... NEJM Review: https