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diagnosis oncology amyloid anemia autoinflammatory comparison dermatology differential e1 lymphocytic management mds myelodysplasia myelodysplastic rheumatology scleroderma somatic syndromes table vacuoles
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or ... Chronic leukemia ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cytometry • Peripheral ... Lymphocytosis: Absolute blood ... aplasia • ITP ... #CLL #Chronic ... workup #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Causes • Anemia • Aplastic ... Marrow Failure • Chronic ... Myelogenous Leukemia ... Cell Leukemia ... #diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... virus (EBV) • Leukemia ... anemia) Labs: • Peripheral ... result from low blood ... Anemia #oncology #hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... (12%) • giant cell ... including peripheral ... blood myeloid cells ... NEJM Review: https
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Bronchiectasis, Chronic ... : • Nephrotic syndrome ... Carpal tunnel syndrome ... Increased plasma cells ... Diagnostic Testing Blood
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
hands and facei peripheral ... lymphocytes, plasma cells ... myeloma or AL amyloidosis ... frequent in men Chronic ... be seen after blood
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