13 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
blasts in the peripheral ... blood smear or ... - Blood and Bone ... develop leukostasis syndrome ... • Tumor lysis syndrome
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... cytometry • Peripheral ... Lymphocytosis: Absolute blood ... aplasia • ITP ... • Richter’s Syndrome
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
Plasmacytomas and Plasma-Cell ... A peripheral-blood ... revealed 25% plasma cells ... Wright–Giemsa stain) #Clinical ... #Smear #NEJM
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
(T-PLL) not Acute ... Myeloid Leukemia ... Prolymphocytes #Smear #Peripheral ... Pathology #Microscopy #Clinical ... #Blood
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
bone marrow and peripheral ... ) Peripheral ... Causes • Anemia • Aplastic ... Chronic Myelogenous Leukemia ... Cell Leukemia
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Anemia Clinical ... virus (EBV) • Leukemia ... anemia) Labs: • Peripheral ... result from low blood
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Clinical suspicion ... Clinical Manifestations ... : • Nephrotic syndrome ... Carpal tunnel syndrome ... Diagnostic Testing Blood
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... (12%) • giant cell ... including peripheral ... blood myeloid cells ... NEJM Review: https
Sickle cells
These photos show sickle cells on peripheral blood smears. In the left photo target cells
cells on peripheral ... blood smears. ... trait do very well clinically ... #Clinical #Path ... #BloodSmear #Blood
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
confusion...A peripheral-blood ... resolve despite blood ... #NEJM #clinical ... spurcell #anemia #peripheral ... #blood #smear