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diagnosis hematology oncology clinical smear bloodsmear chronic lymphocytic mds myelodysplastic path aplastic asplenia autoinflammatory babesia babesiosis derm e1 hemeonc honc
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blasts in the peripheral ... blood smear or ... develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cytometry • Peripheral ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... • Richter’s Syndrome ... syndrome • Smoldering
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
Plasmacytomas and Plasma-Cell ... Leukemia - Physical ... A peripheral-blood ... revealed 25% plasma cells ... #Smear #NEJM
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
bone marrow and peripheral ... cell count (anemia ... ) Peripheral ... Chronic Myelogenous Leukemia ... Cell Leukemia
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
Spur-Cell Anemia ... confusion...A peripheral-blood ... Spur-cell anemia ... #NEJM #clinical ... #peripheral #blood
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... Diagnosis: • Peripheral ... lymphocytes, smudge cells ... 5) Symptoms of anemia ... hemeonc #diagnosis #management
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Abnormalities: macrocytic anemia ... (12%) • giant cell ... including peripheral ... blood myeloid cells ... NEJM Review: https
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... virus (EBV) • Leukemia ... ) Labs: • Peripheral ... result from low blood ... hematology #diagnosis #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... cytopenias (usually anemia ... transformation to acute leukemia ... Allogeneic stem cell
Sickle cells These photos show sickle cells on peripheral blood smears. In the left photo target cells
photos show sickle ... cells on peripheral ... blood smears. ... no significant anemia ... Path #BloodSmear #Blood
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