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diagnosis hematology oncology chronic clinical cll rheumatology smear amyloid amyloidosis anemia aplastic asplenia autoinflammatory bands basophils bloodsmear causes coagulation derm
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blasts in the peripheral ... blood smear or ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Leukemia): • Lymphocytes
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... cytometry • Peripheral ... Lymphocytosis: Absolute blood ... • Richter’s Syndrome ... • Sezary syndrome
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... Diagnosis: • Peripheral ... , smudge cells are ... characteristic • Peripheral ... hemeonc #diagnosis #management
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
and Plasma-Cell Leukemia ... A peripheral-blood ... revealed 25% plasma cells ... Plasmacytomas #PlasmaCell #Leukemia ... #Smear #NEJM
Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
, monocytes, & lymphocytes ... defined as white blood ... circulate freely in peripheral ... blood; The rest ... cell type in the peripheral
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
bone marrow and peripheral ... leukopenia) Peripheral ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... differential • Peripheral
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... hematopoietic stem cells ... including peripheral ... blood myeloid cells ... NEJM Review: https
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... virus (EBV) • Leukemia ... anemia) Labs: • Peripheral ... result from low blood ... hematology #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... glands: • Focal lymphocytic ... neuropathy • Peripheral ... UIP, NSIP): • Lymphocytic ... Rheumatology #Diagnosis #Management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... ABO incompatible blood ... D-Dimer: ↑ • Peripheral ... Schistocytes, helmet cells ... causes #treatment #management
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