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diagnosis hematology mds anemia aplastic autoinflammatory chronic cll e1 lymphocytic myelodysplasia rheumatology somatic syndromes treatment vacuoles vexas workup xlinked
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
bone marrow and peripheral ... leukopenia) Peripheral ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... #hematology #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... = funny-shaped cells ... transformation to acute leukemia ... treatment #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blasts in the peripheral ... blood smear or ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
multiple myeloma, myelodysplastic ... multiple myeloma or myelodysplastic ... including peripheral ... blood myeloid cells ... NEJM Review: https
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cytometry • Peripheral ... Lymphocytosis: Absolute blood ... • Richter’s Syndrome ... • Sezary syndrome ... diagnosis #workup #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
• Hypocellular myelodysplastic ... virus (EBV) • Leukemia ... anemia) Labs: • Peripheral ... result from low blood ... Aplastic #Anemia #oncology
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