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diagnosis hematology oncology bloodsmear clinical aplastic asplenia chronic cll e1 howell howelljollybody jolly lymphocytic mds myelodysplasia myelodysplastic rheumatology schistocytes sickle
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or ... develop leukostasis syndrome ... - infiltrates (anemia ... smear: Blasts ... • Tumor lysis syndrome
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
enzyme, X-linked, Autoinflammatory ... Abnormalities: macrocytic anemia ... including peripheral ... blood myeloid cells ... NEJM Review: https
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
Wright-stained peripheral ... blood smears the ... in the right photo ... thalassemia, and leukemia ... #Clinical #Path
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
bone marrow and peripheral ... Smear: • Dysplastic ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... blood smear •
Sickle cells These photos show sickle cells on peripheral blood smears. In the left photo target cells
cells on peripheral ... blood smears. ... no significant anemia ... #Clinical #Path ... #BloodSmear #Blood
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... In the right photo ... hemolytic- uremic syndromes ... #Clinical #Path ... #Smear #Schistocytes
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cytometry • Peripheral ... smear: Smudge cells ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... • Sezary syndrome
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... virus (EBV) • Leukemia ... ) Labs: • Peripheral ... result from low blood ... hematology #diagnosis #management
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