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diagnosis hematology oncology clinical smear bloodsmear rheumatology anemia aplastic asplenia autoinflammatory chronic derm e1 honc howell howelljollybody jolly lymphocytic mds
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blasts in the peripheral ... blood smear or ... Pruritis after hot bath ... develop leukostasis syndrome ... • Tumor lysis syndrome
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cytometry • Peripheral ... Lymphocytosis: Absolute blood ... • Richter’s Syndrome ... syndrome • Smoldering ... adult T cell leukemia
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
Plasmacytomas and Plasma-Cell ... Leukemia - Physical ... A peripheral-blood ... revealed 25% plasma cells ... #Smear #NEJM
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
bone marrow and peripheral ... ) Peripheral ... Chronic Myelogenous Leukemia ... Cell Leukemia ... differential • Peripheral
Sickle cells These photos show sickle cells on peripheral blood smears. In the left photo target cells
photos show sickle ... cells on peripheral ... blood smears. ... #Clinical #Path ... #BloodSmear #Blood
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
(12%) • giant cell ... hematopoietic stem cells ... including peripheral ... blood myeloid cells ... NEJM Review: https
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
Wright-stained peripheral ... blood smears the ... in the right photo ... thalassemia, and leukemia ... #Clinical #Path
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... virus (EBV) • Leukemia ... anemia) Labs: • Peripheral ... result from low blood ... hematology #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... neuropathy • Peripheral ... 27% for CNS and peripheral ... Pulmonary amyloidosis, PAH ... Rheumatology #Diagnosis #Management
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