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diagnosis differential leukemia agglutinin aplastic autoinflammatory bloodsmear causes chronic clinical cll cold disease e1 elevatedmcv hemolytic lymphocytic macrocytic macrocytosis management
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Differential Diagnosis Algorithm ... Normal Blood Smear ... Myelodysplastic Syndromes ... Macrocytosis, Target Cells ... #Causes #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... cells, red blood ... smear • Bone marrow ... #diagnosis #hematology ... #oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Peripheral Smear ... : Acute blood loss ... hemolysis, deficiency anemia ... Kawasaki, Nephrotic syndrome
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... Abnormalities: macrocytic anemia ... including peripheral blood ... myeloid cells ... NEJM Review: https
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... In the right photo ... seen in hemolytic anemias ... hemolytic- uremic syndromes ... #Smear #Schistocytes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... result from low blood ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
smear or on bone ... - infiltrates (anemia ... • Peripheral smear ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Peripheral smear ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... diagnosis #workup #oncology ... #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... smear - RBC agglutination ... sensitize red blood ... cells (RBCs) at ... #hematology #diagnosis
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