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diagnosis clinical differential management anemia bloodsmear path algorithm leukemia mds myelodysplastic rheumatology schistocytes treatment agglutinin aplastic autoinflammatory babesia babesiosis cancer
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Peripheral Smear ... smear • Bone marrow ... #diagnosis #hematology ... #oncology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... criteria for 1) hematologic ... including peripheral blood ... myeloid cells ... NEJM Review: https
Schistocytes can assume a shape resembling natural or man-made objects such as arrowheads, fish, collar buttons,
In this case, arrows ... seen in the left photo ... In the right photo ... Path #BloodSmear #Blood ... #Smear #Helmet
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Algorithm Normal Blood ... Smear • Drugs ... Myelodysplastic Syndromes ... #Hematology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... neutrophil count < 500 cells ... Superior Vena Cava Syndrome ... : Tumor Lysis Syndrome
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... old, ~10,000 new cases ... Management #treatment #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
smear or on bone ... • Peripheral smear ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Spherocytes - The arrow points to one of many spherocytes in this photo. The cells have
spherocytes in this photo ... The cells have assumed ... This smear was from ...

Causes of spherocyte ... Path #BloodSmear #Blood

Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... In the right photo ... hemolytic- uremic syndromes ... Path #BloodSmear #Blood ... #Smear #Schistocytes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... result from low blood ... Aplastic #Anemia #oncology ... #hematology #diagnosis
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