24 results
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
enzyme, X-linked, Autoinflammatory ... including peripheral blood ... myeloid cells ... NEJM Review: https ... #E1 #Xlinked #Autoinflammatory
Schistocytes can assume a shape resembling natural or man-made objects such as arrowheads, fish, collar buttons,
In this case, arrows ... seen in the left photo ... In the right photo ... Clinical #Path #BloodSmear ... #Blood #Smear #
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... In the right photo ... hemolytic- uremic syndromes ... Clinical #Path #BloodSmear ... #Blood #Smear #
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... by blood cells ... skin that are caused ... Out Secondary Causes ... #diagnosis #hematology
Spherocytes - The arrow points to one of many spherocytes in this photo. The cells have
spherocytes in this photo ... The cells have assumed ...

Causes of spherocyte ... Clinical #Path #BloodSmear ... #Blood #Smear #

Some of the techniques used for Antenatal Diagnosis

Amniocentesis 
 - Chromosome/micro-array and DNA analysis 
 -
— PCR Fetal blood ... serology - Fetal blood ... genetic analysis of cells ... surgery, e.g. laser photo-coagulation ... transfusion syndrome
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Etiology unknown: Autoinflammatory ... • A clinical diagnosis ... Rule out other causes ... , breast bone, pelvis ... #Rheumatology #diagnosis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... - Differential Diagnosis ... Algorithm Normal Blood ... Myelodysplastic Syndromes ... Macrocytosis, Target Cells
Rapid, increasing signs of extrapyramidal symptoms (EPS) is an important key feature of NMS. EPS, associated
about 95% of NMS cases ... (CK) and white blood ... cells. ... #Diagnosis #Serotonin ... #Syndrome #NMS
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
dermatoses are autoinflammatory ... Causes: - Idiopathic ... Leukemia cutis Diagnosis ... neutrophils in the blood ... #diagnosis #dermatology