8 results
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
enzyme, X-linked, Autoinflammatory ... , Somatic) Syndrome ... NEJM Review: https ... #E1 #Xlinked #Autoinflammatory ... #Somatic #rheumatology
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
schizocytes, these cells ... shapes of red cells ... In the right photo ... hemolytic- uremic syndromes ... Clinical #Path #BloodSmear
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Etiology unknown: Autoinflammatory ... lower-extremity joints Diagnosis ... • A clinical diagnosis ... , breast bone, pelvis ... #Rheumatology #diagnosis
Some of the techniques used for Antenatal Diagnosis

Amniocentesis 
 - Chromosome/micro-array and DNA analysis 
 -
for Antenatal Diagnosis ... genetic analysis of cells ... surgery, e.g. laser photo-coagulation ... transfusion syndrome ... Antenatal #Testing #Diagnosis
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
Blood Smear 23M Somali ... Syndrome: 3d of ... LBRF can be diagnosed ... can be used for diagnosis ... #recurrentis #BloodSmear
Tinea Capitis in a Newborn- A 3-week-old male newborn was brought to the pediatrician with three
originally from Somalia ... ringworm, was diagnosed ... #clinical #photo ... #NEJM #tinea #capitis
Causes of Chronic Diarrhea
Osmotic Diarrhea
 1. Medications: antacids, lactulose, sorbitol
 2. Disaccharidase deficiency: lactose intolerance
 3.
Chronic Diarrhea Osmotic ... Zollinger-Ellison syndrome ... Malabsorption syndromes ... Cryptosporidium, Isospora belli ... #Differential #diagnosis
Pyoderma Gangrenosum (PG)
50 M Crohn’s dz had a small pustule on the ankle 4 mo ago
Diagnosis? ... considered an autoinflammatory ... neutrophils & T-cells ... #PG #clinical #photo