15 results
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
enzyme, X-linked, Autoinflammatory ... hematopoietic stem cells ... blood myeloid cells ... NEJM Review: https ... #E1 #Xlinked #Autoinflammatory
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
from shearing, tearing ... shapes of red cells ... In the right photo ... hemolytic- uremic syndromes ... Clinical #Path #BloodSmear
Some of the techniques used for Antenatal Diagnosis

Amniocentesis 
 - Chromosome/micro-array and DNA analysis 
 -
for Antenatal Diagnosis ... genetic analysis of cells ... surgery, e.g. laser photo-coagulation ... transfusion syndrome ... #Antenatal #Testing
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Etiology unknown: Autoinflammatory ... lower-extremity joints Diagnosis ... • A clinical diagnosis ... , breast bone, pelvis ... #Rheumatology #diagnosis
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
Irritable Bowel Syndrome ... (IBS) - Diagnosis ... strategy with minimal testing ... intestinal epithelial cells ... Irritable #Bowel #Syndrome
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myelodysplastic syndromes ... (CML) • Felty Syndrome ... Treatment: Goals: Treating ... #diagnosis #hematology
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing
Common causes: 
 • Renal parenchymal disease
- Differential Diagnosis ... and Screening Testing ... scan of abdomen/pelvis ... • Cushing’s syndrome ... #Differential #Diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Diagnosis: • hemolytic ... Positive Coombs testing ... post infectious setting ... sensitize red blood cells
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
: • Nephrotic syndrome ... Carpal tunnel syndrome ... Increased plasma cells ... Testing Blood ... typing Cardiac Testing
Glandular Tularemia- ...The patient’s physical examination revealed three erythematous, tender lymph nodes...Serologic testing with IgM antibody
nodes...Serologic testing ... A diagnosis of glandular ... 3 conditions, diagnosis ... #NEJM #clinical ... #photo #lymph #Francisella