14 results
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear
Beautiful acanthocytes/spur cells in a patient with McLeod Syndrome. X-linked disorder characterized by reduced expression of
acanthocytes/spur cells ... patient with McLeod Syndrome ... SpurCells #McLeod #Syndrome ... #Smear #Pathology
Urinary Tract Tuberculosis - Contrast-enhanced computed tomography (CT) of the abdomen showed mild dilatation of the
the left renal pelvis ... Clinical #Radiology #Pathology ... AcidFastBacilli #Microscopy #NEJM
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... myelodysplastic syndrome ... hematopoietic stem cells ... blood myeloid cells ... NEJM Review: https
Castleman's Disease and Associated Syndromes
HYALINE VASCULAR VARIANT
 • unicentric, HHV8-ve, children and young.
 • Hyalinized vessels
and Associated Syndromes ... Diffuse plasma cells ... Pathogenesis "IL6 syndrome ... Variants #Diagnosis #Pathology
Cryptococcus neoformans Meningoencephalitis- The opening pressure on lumbar puncture was 29 cm of water (reference range,
count was 340 cells ... 90% mononuclear cells ... CD4+ count was 7 cells ... #clinical #NEJM ... stain #indiaInk #pathology
Marfan’s Syndrome with Ectopia Lentis - Slit-lamp examination revealed ectopia lentis in both eyes, including near-complete
Marfan’s Syndrome ... with Ectopia Lentis ... revealed ectopia lentis ... LensDislocation #SlitLamp #NEJM
Some of the techniques used for Antenatal Diagnosis

Amniocentesis 
 - Chromosome/micro-array and DNA analysis 
 -
genetic analysis of cells ... surgery, e.g. laser photo-coagulation ... transfusion syndrome
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood cells ... schizocytes, these cells ... shapes of red cells ... In the right photo ... hemolytic- uremic syndromes
Dubin-Johnson Syndrome - A laparoscopic exploration revealed a smooth liver with normal consistency and morphologic features
Dubin-Johnson Syndrome ... B) #Clinical #Pathology ... #DubinJohnson #Syndrome ... #Microscopy #NEJM