11 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
AIHA Primary Secondary ... lymphoproliferative disorder Secondary ... Syndrome (CAS): ... anemiaCold ... sensitize red blood cells
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Diseases Nail Fold ... Iron deficiency anemia ... • Nephrotic syndrome ... #Differential #Diagnosis ... #Algorithm #causes
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
patients < 50 yrs old ... - Normocytic Anemia ... - Giant cells ... Temporal #Arteritis #Pathophysiology ... #Diagnosis #Signs
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... Anticonvulsants - Gold ... • Improve the symptoms ... oncology #hematology #diagnosis
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Algorithm - Systemic ... renal failure/uremia ... Myelodisplastic syndrome ... Psychiatric Disease ... Pruritus #primary #secondary
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... DDX: Rule Out Secondary ... Causes • Anemia ... • Aplastic Anemia ... #diagnosis #hematology
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Refeeding Syndrome ... PO4 and Mg into cells ... hemolysis - anemia ... #diagnosis #pathophysiology ... #symptoms #signs
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome ... bone marrow and secondary ... Hematology #Oncology #Diagnosis
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Algorithm Blood ... renal failure/uremia ... Myelodisplastic syndrome ... Psychiatric Disease ... #Pruritus #secondary
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
lymphocytosis, mild anemia ... Hypothermia and Cold ... Complications #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry