14 results
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... phase symptoms Signs ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis ... #signs #symptoms
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
cytokine synthesis, e.g ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology ... #immunology
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
Lipid mediators (e.g ... Other mediators (e.g ... of inflammatory cells ... #Anaphylaxis #pathophysiology ... #immunology
A Lewis Lead (also called the S5 lead) is a modified ECG lead used to detect
is a modified ECG ... clinically, based on signs ... standard 12 lead ECG ... Lead I on the ECG ... #Cardiology #EKG
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Signs of immunodeficiency ... humoral immunity Signs ... bacterial infections (e.g ... Agammaglobulinemia #XLinked #pathophysiology ... #immunology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Ag-presenting cells ... or plasma cells ... storage sites (e.g ... Humoral #Immunity #pathophysiology ... #immunology
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
alpha-1 blockers (e.g ... -5 inhibitors (e.g ... testicular Leydig cells ... Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells ... unless worrisome EKG
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... of UMN and LMN signs ... both UMN and LMN signs ... EMG: LMN Signs in
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... inotropy) ACCP Cardiology ... Antiarrhythmics #Pharmacology ... Classification #Classes #pathophysiology ... #phases #cardiology