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management diagnosis hivaids infections opportunistic prevention cardiology classes classification rheumatology syndrome capsulatum coagulation dic disseminated hemophagocytic histoplasma histoplasmosis hlh intravascular
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
Antiarrhythmics ... ++ influx into cells ... Vaughan #Williams #Pharmacology ... Classification #Classes ... #pathophysiology
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
Antiarrhythmics ... Pharmacology Summary ... #Pharmacology # ... Classification #Classes ... #pathophysiology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells ... diagnosis #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Drugs, Unknown cause ... Treatment: • ... diagnosis #management #treatment ... #summary #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Xerostomia • Dental caries ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... lubricants • Pharmacologic
IDSA Recommendations for Preventing and Treating Histoplasma Capsulatum Infections in HIV-AIDS Indications for Initiating Primary Prophylaxis: •
IDSA Recommendations ... histoplasmosis (>10 cases ... Histoplasmosis #IDSA ... #Prevention #Treatment ... infections #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Managing Microsporidiosis in HIV-AIDS Preventing Chronic Microsporidiosis: • Because chronic microsporidiosis occurs
IDSA Recommendations ... CD4 count >100 cells ... Gastrointestinal Infections Caused ... Microsporidiosis #IDSA ... infections #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Treating Varicella Zoster Virus (VZV) Infections in HIV-AIDS Pre-Exposure Prevention of VZV
IDSA Recommendations ... CD4 count ≥200 cells ... Uncomplicated Cases ... #Zoster #VZV #IDSA ... infections #HIVAIDS #pharmacology
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