19 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... With associated pulmonary ... involvement: Anti-GBM Disease ... Glomerulonephritis #Vasculitis
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Summary Kawasaki ... the most common vasculitis ... , Cough • +/-Nausea ... #KD #vasculitis ... #rheumatology #
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... Summary Epidemiology ... extrapulmonary cases ... decreased reflexes Pathophysiology ... #Summary
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
progressing GN • New pulmonary ... Multinucleated giant cells ... MPO > PR3) • Pulmonary ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager Summary ... Autoimmune ANCA vasculitis ... life-threatening diseases ... Goodpasture's cause ... differential #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... • Autoimmune diseases ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Summary Lung ... Lung Abscess Pathophysiology ... Diagnosis: • Vasculitis ... Lung #Abscess #pulmonary ... #differential #causes
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
: • 10%-15% Pulmonary ... , INC risk PE, Pulmonary ... ) • Cutaneous vasculitis ... Nephrogenic DI Hematologic ... #Diagnosis #Management
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Summary ... malignancies, vasculitis ... thrombophlebitis, pulmonary ... cryoglobulins • Negative causes ... #hematology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Summary A defect ... Caused by intrapulmonary ... cirrhosis • Intra-pulmonary ... perfusion scanning or pulmonary ... #treatment #hepatology