32 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Neutropenia - recurrent infections ... Idiopathic • Infections ... #oncology #hematology
IDSA Recommendations for Preventing and Treating Penicillium marneffei Infections in HIV-AIDS
Preventing 1st Episode of Penicilliosis (Primary
Penicillium marneffei Infections ... CD4 count <100 cells ... Treating Acute Infection ... opportunistic #infections ... #HIVAIDS #pharmacology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
• Symptoms of anemia ... • hemolytic anemia ... sensitize red blood cells ... disease #hemolytic #anemia ... #hematology #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... cytopenias (usually anemia ... risk-stratification • Risks: infection ... Management #treatment #hematology
IDSA Recommendations for Treating Isospora belli Infection in HIV-AIDS
Treating Isospora belli Infection
General Management Considerations:
 • Fluid
Treating Isospora belli ... Infection in HIV-AIDS ... Treating Isospora belli ... Infection General ... #HIVAIDS #pharmacology
Non-cirrhotic Hyperammonemia - Differential Diagnosis Framework

Hematologic & Vascular:
 • Multiple myeloma & Acute leukemia (plasma cells
Diagnosis Framework Hematologic ... leukemia (plasma cells ... Malformation) Infections ... loading) - Infections ... Differential #Diagnosis #Pathophysiology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
predictive of a serious infection ... overlook severe infections ... superior indicator of infection ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle cells ... inclusions - If infection ... ARUPLabs #Hemolytic #Anemia ... Algorithm #workup #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Triggering factor (infection ... Activation of CD8 T cells ... Phagocytosis of blood cells ... treatment #summary #rheumatology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Neoplastic / Hematologic ... • Anemia • ... Malignancy Infectious ... Myasthenia Gravis Pharmacologic