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diagnosis nephrology syndrome algorithm als amyotrophic apml cancer causes chloride differentiation emergencies gitelman hematology hypochloremia hypokalemia lateral myelitis oncologic rhabdomyolysis
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential ... of breath • Neurologic ... neutrophil count < 500 cells ... mental function • Weakness ... #differential #
Hypochloremia - Differential Diagnosis Algorithm Cause - Decreased Intake: • Low salt in diet • Exclusive D5W
Hypochloremia - Differential ... SIGNS: • Muscle weakness ... smooth muscle cells ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... bulbar region, Weakness ... conditions listed in differential ... Lateral #Sclerosis #neurology ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... Release from blast cells ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Framework and Management ... Muscle pain - Weakness ... kidney tubular cells ... #Diagnosis #Management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Weakness: - Weakness ... Pleocytosis > 100 cells ... Myelitis #diagnosis #management ... #neurology #differential
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... affects the skin, neurologic ... Myalgia and muscle weakness ... cognitive impairment, neurologic ... (PR3-ANCA)): Microscopic
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
apical membrane of cells ... Fatigue • Muscle weakness ... ratio 0.5%) Differential ... Syndrome #diagnosis #nephrology ... #management #pathophysiology
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