9 results
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
Immune Reactions ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology ... #immunology
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Mechanism of Action ... #Medications #pharmacology ... #pathophysiology ... #endocrinology
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... Mechanisms of Action ... pancreatic beta cells ... Sulfonylureas #Pharmacology ... DM2 #diabetes #endocrinology
Anastrozole is a Selective non-steroidal aromatase Inhibitor. Used for the treatment of breast cancer in postmenopausal
Mechanism of action ... derived from the action ... and in cancer cells ... #pharmacology #overview ... druginformation #treatment #endocrinology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
, Intermediate Action ... Blockade, Fast Action ... ++ influx into cells ... Vaughan #Williams #Pharmacology ... Classification #Classes #pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... , Intermediate Action ... Blockade, Fast Action ... Antiarrhythmics #Pharmacology ... Classification #Classes #pathophysiology
Bone resorption and the relationship between osteoblasts and osteoclasts.  
RANK is expressed on the osteoclasts,
expressed on marrow cells ... the ECF, wherein reactions ... released through the actions ... #Pathophysiology ... #Endocrinology
Insulin Calculations for Type 1 Diabetes 

Insulin-to-Carb Ratio (ICR) 500/TDD = #g of carbs covered by
unit of rapid-acting ... unit of rapid-acting ... The ICR tells us ... Diabetes #DM1 #Pharmacology ... #Endocrinology
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
Adrenoceptor Actions ... • Pancreatic ß-cells ... adrenergic #receptors #actions ... #pharmacology # ... pathophysiology