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allergy antiarrhythmics cardiology classes classification adrenergic adrenoceptor comparison drugs immunosuppressant phases receptors table type1 type2 type4 typei typeiv vaughan williams
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
harmful -> Th Cells ... macrophages, mast cells ... TypeIV #Type4 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Immune Reactions and Immunosuppressant Drugs Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2 Muromonab-CD3 - Monoclonal antibody Calcineurin
Immune Reactions ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology ... #immunology
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
body cell -> B-Cells ... foreign -> B-cells ... #Type2 #Type2 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
complexes bind to mast cells ... • Inflammatory cells ... #TypeI #Type1 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
, Intermediate Action ... Blockade, Fast Action ... ++ influx into cells ... Vaughan #Williams #Pharmacology ... Classification #Classes #pathophysiology
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... , Intermediate Action ... Blockade, Fast Action ... Antiarrhythmics #Pharmacology ... Classification #Classes #pathophysiology
Adrenoceptor Actions α1 • Vascular smooth muscle - Contraction • Genitourinary smooth muscle - Contraction • Intestinal
Adrenoceptor Actions ... • Pancreatic ß-cells ... adrenergic #receptors #actions ... #pharmacology # ... pathophysiology
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