19 results
classification antiarrhythmics cardiology classes hypersensitivityreaction medications endocrinology humoral management table acid adrenergic adrenoceptor allergicrhinitis anaphylaxis antihistamines asthma benign bileacid biliary
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
Allergic reaction ... Particular CD4+ Th cells ... harmful -> Th Cells ... macrophages, mast cells ... #Immunology #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... plasma cells that ... complexes bind to mast cells ... • Inflammatory cells ... #Immunology #pathophysiology
Immune Reactions and Immunosuppressant Drugs Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2 Muromonab-CD3 - Monoclonal antibody Calcineurin
Immune Reactions ... Basiliximab - IL-2 receptor ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology ... #immunology
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
Antigen binds receptor ... foreign -> B-cells ... the cell surface receptor ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Anaphylaxis: Treatments (Acute) Additional Info: • IV steroids may be considered for prevention of late phase reactions.
of late phase reactions ... provided, as well as allergy ... • H2 receptor ... Treatments #Management #pathophysiology ... #immunology
Mechanism of Action for Common Diabetes Medications • SGLT2i (Dapagliflozin) • TZD (Pioglitazone) • Biguanides (Metformin)
Mechanism of Action ... Meglitinides • GLP-1 Receptor ... #Medications #pharmacology ... #pathophysiology
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
via their Fc receptor ... When the specific allergen ... Classification #Pathophysiology ... #Allergy #Diagnosis ... #Reactions #Table
Mechanism of Action of Bile Acid Sequestrants Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Mechanism of Action ... Production → ↑ LDL Receptors ... sequestration #pathophysiology ... #pharmacology #
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
Activated T cells ... to the B-cell receptor ... to the T-cell receptor ... ImmuneResponses #immunology ... #pathophysiology
Inflammatory mechanism of asthma. Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Airway epithelial cells ... These T cells then ... binds the FceRI receptor ... #asthma #pathophysiology ... #inflammatory #immunology
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