25 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Prednisone 5mg/kg ... initiation • Differential ... #management #hematology
Causes of Excessive Daytime Sleepiness - Differential Diagnosis Algorithm
Insufficient Sleep
 • Poor Sleep Hygiene
 • Insomnia
Sleep Deprivation (Eg ... Disorders • Neurologic ... Disorders (Eg. ... • Medications (Eg ... • Drug Abuse (Eg
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... treatment #hematology #differential
Approach to ECGs - Tachy/Bradyarrhythmias
Tachyarrhythmias - HR > 100
Wide
  (1) VT - DANGER
  (2)
(2) Sick Sinus Syndrome ... bradyarrhythmia #ECG ... #EKG #diagnosis ... electrocardiogram #cardiology ... #differential
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Surgical devices, e.g ... Sepsis (→ 3-14) e.g ... (e.g. haloperidol ... Phaeochromocytoma Neurologic ... #Hyperthermia #Differential
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... (both ALL and AML ... with Ca only if EKG ... Walid Malki, MD, MS ... TLS #oncology #management
STEMI Equivalents on ECG
 • Conventional STEMI - Elevation of ST segment at (or 40-60 ms
Equivalents on ECG ... point • De Winter syndrome ... #Equivalents #ECG ... #EKG #diagnosis ... #differential #
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... : • Pathophysiology ... Lysis of tumor cells ... unless worrisome EKG ... TLS #diagnosis #management
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
BEE Syndromes - ... skull neoplasms (e.g ... consistent with MS ... #neurology #noninflammatory ... #differential #
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Pathophysiology ... unit activity on EMG ... of diazepam • EMG ... TPO, TTG, etc EMG ... #treatment #neurology