14 results
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... meningococcal, H1N1) Clinical ... Clinical Features ... Electrodiagnostic studies - EMG
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Pathogenesis and clinical ... harmful -> Th Cells ... Stevens-Johnson Syndrome ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... transplantation CLINICAL ... the underlying pathophysiology ... specific therapy, the clinician ... #Syndrome #diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... : • Pathophysiology ... Lysis of tumor cells ... unless worrisome EKG ... diagnosis #management #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Aplastic Anemia Clinical ... Constitutional Syndromes ... CMV) • Epstein-Barr ... Anemia #oncology #hematology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Pathogenesis and clinical ... from precursor cells ... bacterial infections (e.g ... Agammaglobulinemia #XLinked #pathophysiology ... #immunology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Pathogenesis and Clinical ... or plasma cells ... storage sites (e.g ... Humoral #Immunity #pathophysiology ... #immunology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... infections (Epstein-Barr ... syndrome, HIV) ... hypogammaglobulinemia #immunology ... #hematology #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... Diagnosis: • A clinical ... , breast bone, pelvis ... antiinflammatory properties e.g ... #Rheumatology #