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diagnosis management rheumatology oncology differential signs symptoms smear treatment causes neurology erythematosus hepatology leukemia lupus microscopy sle systemic algorithm blood
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... • Sickle cells ... alcoholism • Burr cells ... Hemolytic uremic syndrome ... #differential #hematology
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Sickled red cells ... disease Bite cells ... Smear #Analysis #hematology ... interpretation #clinical ... #anemia
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... vasculitis • Hematologic ... Abnormalities: macrocytic anemia ... criteria for 1) hematologic
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Clinical Presentation ... Constitutional Syndromes ... marrow-failure syndromes ... #oncology #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Pernicious Anemia ... Myelodysplastic Syndromes ... Macrocytosis, Target Cells ... Algorithm #Causes #Hematology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic anemia ... DIC is a clinical ... Microangiopathic hemolytic anemia ... polychromatophilic cells ... #Hematology #Pathology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... Management #treatment #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... • Aplastic Anemia ... Megaloblastic Anemia ... Myelophthisic Anemia ... #diagnosis #hematology
A non-subtle example of true Sezary syndrome. Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... Smear #Microscopy #Hematology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Anemia is described ... the red blood cells ... Pancytopenia is a hematologic ... well as varying clinical
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