10 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... • Pulmonary: pleural ... effusion, infiltrates ... Disease #diagnosis #management ... #treatment #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
that disrupts immune ... accumulation of clinical ... Assessment • Clinical ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
of hands/feet, knees ... nodules, joint effusions ... Ultrasound Diagnosis: CLINICAL ... exam and imaging Treatment ... #rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
mutations) • Immune ... Aplastic Anemia Clinical ... HCV - HIV • Immune ... aplastic anemia Treatment ... #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
noncompliance • Clinical ... initiation Clinical ... pulmonary infiltrates, pleural ... effusions, CNS ... Differential #Diagnosis #Management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Erythema nodosum • Immune ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
ducts Clinical ... Xerotrachea • NSIP: Pleural ... thickening or effusion ... phenomenon (16%) MSK ... #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Progression: (+) Immune ... rest LTBI (-) Immune ... characteristic features Clinical ... organ system: • Pleura ... TB #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Progression: (+) Immune ... rest LTBI (-) Immune ... characteristic features Clinical ... organ system: • Pleura ... TB #Diagnosis #Management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
activation of an immune ... mediated disease • Immune ... Transverse Myelitis - Clinical ... Transverse Myelitis Treatment ... Myelitis #diagnosis #management