6 results
HHV8/KSHV-reIated diseases: From Cellular Proliferation to Hyperinflammation
Kaposi sarcoma (KS):
 • Target organs: Ubiquitous (cutaneous and mucosal
HHV8/KSHV-reIated ... Light chain: - HHV8 ... lymphoma (PEL): ... Target organs: Pleural ... , pericardial, peritoneal
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
that disrupts immune ... accumulation of clinical ... Virus (EBV, CMV, HHV8 ... , B-cell lymphoma ... Lymphohistiocytosis #diagnosis #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
ducts Clinical ... Xerotrachea • NSIP: Pleural ... thickening or effusion ... phenomenon (16%) MSK ... Adenocarcinoma Treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Sarcoidosis • Lymphoma ... characteristic features Clinical ... organ system: • Pleura ... Skeletal system • Pericardium ... TB #Diagnosis #Management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
initiation Clinical ... pulmonary infiltrates, pleural ... effusions, CNS ... Kaposi sarcoma, HHV8 ... Differential #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Sarcoidosis • Lymphoma ... characteristic features Clinical ... organ system: • Pleura ... Skeletal system • Pericardium ... TB #Diagnosis #Management