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diagnosis hematology causes hemolytic blood cold daytime disease fatigue hypokalemia management markers myelitis nephrology sleepiness transverse workup
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... • hemolytic anemia ... Positive Coombs testing ... younger pts) Differential ... sensitize red blood cells
Causes of Excessive Daytime Sleepiness - Differential Diagnosis Algorithm Insufficient Sleep • Poor Sleep Hygiene • Insomnia
Causes of Excessive ... Daytime Sleepiness - Differential ... Diagnosis Algorithm ... • Neurologic ... Parkinson's, MS)
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... • Sickle cells ... Agglutination - Cold agglutinins ... Consider RBC membrane disorder ... workup #hematology #testing
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... Pelger-Huet, Macrocytic anemia ... or λ), Smudge Cells ... Amy Chung, MD, MSc
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
disorders GI Losses ... Licorice ingestion, Excessive ... megaloblastic anemia ... Hypokalemia #Causes #differential ... #diagnosis #nephrology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Focal inflammatory disorder ... Myelitis: • Excessive ... Pleocytosis > 100 cells ... diagnosis #management #neurology ... #differential
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