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diagnosis hematology causes hemolytic blood chronic cold daytime disease excessive markers sleepiness testing workup
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... include fatigue ... • hemolytic anemia ... younger pts) Differential ... sensitize red blood cells
Causes of Excessive Daytime Sleepiness - Differential Diagnosis Algorithm Insufficient Sleep • Poor Sleep Hygiene • Insomnia
Daytime Sleepiness - Differential ... Diagnosis Algorithm ... • Neurologic ... Parkinson's, MS) ... Excessive #Daytime #Fatigue
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... Pelger-Huet, Macrocytic anemia ... or λ), Smudge Cells ... Amy Chung, MD, MSc
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
- Differential ... Diagnosis Algorithm ... Hematologic • Anemia ... Pulmonary Disease Neurologic ... • Somatization Disorder
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... • Sickle cells ... Agglutination - Cold agglutinins ... Consider RBC membrane disorder
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