16 results
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
exertion • Neurologic ... : Bell's palsy, ... dysrhythmias • Ophthalmologic ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in all cells ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
Pathogenesis and Ocular ... #Xeropthalmia #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms
Orbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Chemosis: Edema of the bulbar conjunctiva
b. Panopthalmitis: inflammation of all
Impaired extra-ocular ... Orbital #Cellulitis #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... prognosis • Nodular ... pattern of spread, B symptoms ... Classification #pathophysiology ... #Hematology #Diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis of tumor cells ... Syndrome #TLS #diagnosis ... #management #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... meningitis), MCC CNS symptoms ... inhibitors • Uveitis- Ophthalmology ... #management #signs ... #symptoms #rheumatology
Periorbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Dacryoadenitis: infection of the lacrimal glands
b. Conjunctivitis: inflammation of the
normal: - extra-ocular ... Periorbital #Cellulitis #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... fasciculations Common Symptoms ... EMG: LMN Signs in ... Lateral #Sclerosis #neurology
Photophobia and Headache - Differential Diagnosis Framework

Why?
• The coexistence of photophobia and headache suggests the potential
- Autonomic symptoms ... meningeal irritation signs ... glaucoma - Ocular ... #ophthalmology ... #Neurology