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diagnosis syndrome oncology als amyotrophic apml cancer differentiation emergencies encephalopathy fatty gitelman hepatology hypokalemia lateral liver myelitis nephrology obgyn obstetrics
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... infiltration) Differential ... iMedEducation #AFLP ... #pathophysiology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... myalgias, HoTN, edema ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Emergencies - Differential ... Diagnosis Framework HEMATOLOGIC ... of breath • Neurologic ... neutrophil count < 500 cells ... Syndrome: • Facial edema
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Etiology: • Pathophysiology ... Reversible course Differential ... Syndrome #diagnosis #management ... #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Microglial cells ... conditions listed in differential ... Lateral #Sclerosis #neurology ... #diagnosis #management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Pleocytosis > 100 cells ... Myelitis #diagnosis #management ... #neurology #differential
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
apical membrane of cells ... ratio 0.5%) Differential ... Syndrome #diagnosis #nephrology ... #management #pathophysiology
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