22 results
Spontaneous Bacterial Peritonitis 
Clinical 
 • Fever 
 • Chills 
 • Abdominal pain 
Diagnosis
Peritonitis Clinical ... Abdominal pain Diagnosis ... • PMN > 250 cells ... stain/culture Management ... #Hepatology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... and Management ... adsorption onto cancer cells ... #Management #treatment ... #hematology #differential
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
type (B cell, T cells ... natural killer (NK) cells ... Diagnosis of B-Symptoms ... #differential # ... hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from mature B cells ... Hodgkin Lymphoma - Clinical ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... number of CD34+ cells ... number of CD34+ cells ... Number of CD34+ cells ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 T cells ... Phagocytosis of blood cells ... accumulation of clinical ... Assessment • Clinical ... #management #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Release from blast cells ... opacities • Diagnosis ... initiation • Differential ... Diagnosis: Infection ... #management #hematology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... Too many cells in ... Better call hematology ... always a good idea ... #workup #hematology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Related Disease Clinical ... PET-CT Imaging (→ Diagnostic ... increased IgG4+ cells ... #management #phenotypes ... workup #treatment #rheumatology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
- Microglial cells ... are the immune cells ... conditions listed in differential ... between nerve cells ... #management